- Design and conduct studies examining cancer progression, metastasis, organ development, and tumor-microenvironment interactions.
- Establish and maintain 2D and 3D cultures, including multicellular co-cultures, organoids, and matrix-embedded cell models.
- Process human or mouse tissues and isolate, culture, and characterize primary cells.
- Develop bioengineered tissue models using hydrogels, microfluidics, organ-on-chip technologies, or related platforms.
- Investigate cellular mechanotransduction and responses to matrix stiffness, architecture, and applied forces.
- Perform quantitative microscopy and image analysis using confocal microscopy, live-cell imaging, and other advanced imaging methods.
- Conduct molecular and cellular assays to characterize cell phenotype, signaling, and gene expression.
- Analyze and interpret experimental data using appropriate statistical and computational methods.
- Prepare manuscripts, presentations, fellowship applications, and contributions to research proposals.
- Collaborate across engineering, cancer biology, and clinical research teams and mentor graduate and undergraduate researchers.
Knowledge, Skills, and Abilities (KSAs):
- Strong written and oral communication skills and the ability to work effectively within an interdisciplinary team.