Clinical Cellular Immunologist

• Summarize the primary purpose & key accountabilities of the position, including scope of responsibility in 5-7 concise sentences. (i.e. Global vs. Country/Region) It may be helpful to complete this section after you have finished the other sections of the document.

• Pharmaceutical Vaccine Immunotherapeutics (VITx) seeks to develop Client vaccines for the treatment of cancer and other significant human diseases using a variety of vaccine technology platforms combined with immunomodulatory agents.

• A Contractor is required to work in the VITx Clinical Cell-Based Assay group, conducting clinical assays under (Good Clinical Laboratory Practice) GCLP-compliance using samples from early stage (Phase I and II) clinical studies.

• Experience of working in a tissue culture laboratory conducting cell biology or immunological assays is required.

• Experience in conducting flow cytometry, plate-based immunological assays (ELISPOT, ELISA, Luminex, etc) and/or working with human clinical samples would be advantageous but is not essential as training will be given.

• Requires good laboratory skills, attention to detail and an ability to accurately and diligently complete laboratory tasks, as well as to document and analyse data.

• The role also includes conducting supporting tasks required to operate a compliant laboratory that may include maintenance of equipment, assistance in reagent sourcing and tracking, as well as other activities relating to maintaining compliance (such as document management).

• Requires the ability to multitask and work under pressure as part of a cohesive and proactive team that is required to meet business-critical deadlines.

POSITION RESPONSIBILITIES 

• In order of importance, list the primary responsibilities critical to the performance of the position. It is recommended not to list actual tasks but focus on essential responsibilities that highlight accountability and level of judgment required.

• Primary responsibility of supporting the conduct of cell-based immunoassays (ELISPOT or flow cytometry-based) on clinical samples following standard operating procedure (SOPs), with accountability for the quality of this analysis.

• Will also be responsible for supporting the operation of the laboratory in accordance with GCLP by conducting equipment maintenance, calibration and/or ordering and tracking reagents.

• Will be required to complete (and maintain thereafter) training in order to conduct assays within a BSL2 clinical assay laboratory in a safe and compliant manner.

• Will build experience in key assay platforms (including flow cytometry and plate-based clinical assays assays) through appropriate training and guided learning.

• Will assist more senior colleagues in at least one of the following: sample management; maintaining human control cell banks; developing new assays; and/or implementing automated assay solutions in the laboratory.

EDUCATION AND EXPERIENCE

Bachelors degree with up to 3 years of relevant work experience, or

Masters degree with up to 1 year of relevant work experience.

TECHNICAL SKILLS REQUIREMENTS

Experience in working in a tissue culture laboratory conducting cell biology or immunological assays.

Proficient using Microsoft Office programs (Word, Excel, PowerPoint, Outlook) and familiarity with both PC and Macintosh computer systems.

Preferred

Experience in working with human samples and isolating human PBMC.

Cell-based assay development experience.

Experience in conducting plate- and/or flow cytometry- based cellular immune assays.

Experience of working in a GxP-compliant environment within the pharmaceutical industry.

Experience with tissue culture and immune assays. Experience with clinical samples. Experience of working in Industry in a GXP compliant environment preferred. Familiarity with cellular Immune assays such as ELISPOT and FACs-based assays preferred. Organized with experience of laboratory or sample management preferred.

Best Regards,

Anuj Mehta

973-967-3402