Director, Precision Medicine Strategy

As Director, Precision Medicine Strategy, you will lead cross-indication strategy and planning for the US Precision Medicine portfolio. Reporting to the Senior Director, Precision Medicine Strategy & Effectiveness, you will own tumor and biomarker strategy, prioritization, and launch readiness, and lead the team supporting biomarker-driven launches and upstream planning.

Working in close partnership with Franchise Heads, Global Diagnostics, Medical Diagnostics, Access, Insights & Analytics, and the Lab Ecosystem & Diagnostic Partnerships Director, you will translate strategy into lab-readiness priorities and ensure the organization focuses on the highest-value launches.

Key Responsibilities

Strategy & Prioritization

• Lead cross-indication precision medicine strategy and planning for the US portfolio.

• Own tumor and biomarker strategy, portfolio prioritization, and launch readiness for Lung, Breast, GI/Heme, and G2 oncology.

• Anticipate biomarker and testing requirements and recommend investments for the highest-value launches.

Team Leadership

• Lead three tumor-type Sr. Associate Directors (Lung, Breast, and GI/G2/Heme) and the Associate Director, PM Strategy, setting objectives, ensuring consistent launch-readiness plans, and developing talent.

• Establish common planning frameworks and the PM Launch Playbook with the Senior Director.

Lab & Cross-Functional Alignment

• Translate strategy into lab-readiness priorities with the Lab Ecosystem & Diagnostic Partnerships Director.

• Align global and US initiatives, and influence Brand, Medical, Access, and Field leaders through data-driven recommendations.

• Represent PM Strategy in franchise, brand planning, and forecasting forums.

Compliance & Governance

• Ensure all activities are conducted in accordance with AstraZeneca policies, Code of Ethics, SOPs, and applicable regulatory requirements.

• Maintain high standards of scientific integrity, compliance, and patient-centered execution.

Essential Qualifications

• Bachelor's degree in Life Sciences, Healthcare, Business, Marketing, or related field.

• Minimum of 10 years of progressive oncology, precision medicine, and diagnostics experience in pharmaceutical or diagnostics settings.

• Leadership of biomarker-driven launches or PM strategy.

• Knowledge of companion diagnostics, molecular testing, and adoption barriers.

• People leadership experience.

• Proven ability to influence in a matrix environment.

Preferred Qualifications

• MBA, MS, PharmD, PhD, or other advanced degree.

• Experience across multiple tumor types or simultaneous launches.

• Experience in global or franchise roles.

Leadership Expectations

The successful candidate will demonstrate:

• Strategic thinking and a strong commercial mindset.

• Ability to translate complex science into strategy.

• Talent development.

• Launch excellence.

• Passion for advancing precision medicine.

Scope of Responsibility

This role leads PM strategy for all biomarker-driven launches across the US oncology portfolio, including Gold-tier launches.

The annual base pay for this position ranges from 193,898.40 - 290,847.60 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

13-Nov-2026

Closing Date

19-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.