Research Scientist – Nucleic Acids Chemistry R&D

Centrillion Biosciences is seeking a creative, energetic, resourceful organic chemist to join a multidisciplinary research team developing new technologies for nucleic acid sequence analysis.

Duties:

• Plan and execute applied research experiments involving:
• Synthesis, modification and characterization of modified nucleotides, nucleoside polyphosphates and oligonucleotides
• Preparation of fluorescent dye conjugates of nucleotides and oligonucleotides.
• Materials modification and characterization for solid phase synthesis
• Collaborate with and/or supervise other scientists & engineers on joint projects.
• Documentation of experimental work; analysis of data; documenting and presenting results
• Preparation of written methods and SOPs
• Operation and maintenance of laboratory & analytical equipment
• Support R&D and Pilot Manufacturing Operations and QC

• PhD in organic chemistry, with extensive training and practical laboratory experience in organic synthesis, physical organic and bioorganic chemistry.
• Experience with nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
• Experience preparing fluorescent dye conjugates of nucleotides and oligonucleotides.
• Proficiency in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
• Working knowledge and practical experience with polymer and surface chemistry is strongly desired.
• Demonstrated ability to plan and execute independent and collaborative research projects.
• Demonstration of goal-oriented, hands-on and innovative approach to problem solving.
• Excellent written and oral communication skills.
• Co-authorship on one or more publications in peer-reviewed scientific journals.
• She/he will be required to develop additional competencies, and apply practical skills and knowledge to solving a variety of applied scientific and technical problems.

All your information will be kept confidential according to EEO guidelines.