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    GondolaBio Service Co, Inc.

    Biotechnology

    Principal Scientist, In Vivo Pharmacology, Neurology

    Any, United StatesRemoteFull-timePosted Yesterday
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    Job description

    Principal Scientist, In Vivo Pharmacology, Neurology

    Remote U.S. or Palo Alto, CA

    About GondolaBio

    GondolaBio is a clinical-stage biopharmaceutical company focused on developing breakthrough therapeutics for genetic diseases. GondolaBio is an independent sister company to BridgeBio, originally carved out in 2024 after securing $300M in private financing from external investors. GondolaBio aims to leverage cutting-edge biological research to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases.

    Who You Are

    You are an experienced in vivo pharmacology scientist with expertise in Neurology. You have demonstrated success in developing and/or applying in vivo disease models to drug discovery campaigns. You have extensive hands-on experience with rodent Neurology model characterization, test article dosing, tissue processing, and common wet lab techniques (e.g. qPCR, Western blot, ELISA). You are execution-oriented, capable of driving work through CROs and external partners, and thrive in a fast-paced biotech environment.

    Key Responsibilities

    • Design and execute on in vivo pharmacology studies across multiple Neurology programs in our research portfolio in rodents and non-human primates, with goals of IND submission.
    • Partner with toxicology and translational teams to ensure our in vivo pharmacology data package is rigorous, reproducible, and translatable — directly informing dose selection and go/no-go decisions.
    • Develop and implement pharmacodynamic and efficacy assessments, troubleshoot assays, and QC data from CROs and external partners.
    • Manage CRO relationships and monitor study progress for ongoing studies, identifying emerging risks, while presenting progress updates in team meetings.
    • Analyze data from in vivo pharmacology endpoints including PK/bioanalysis and pharmacodynamic and/or efficacy endpoints.

    Job details are sourced from the employer's original posting.

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    About the company

    GondolaBio Service Co, Inc.

    This company is involved in clinical pharmacology and early clinical development, focusing on early clinical sciences and development strategy from first-in-human through Phase 2. They also lead quantitative sciences including data analytics, pharmacometrics, biostatistics, and data management to inform dose selection and program development.

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    Industry
    Biotechnology
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