• The scientist will be involved in establishing methodologies, i.e. culturing and activating primary T-cells, enriching T-cell populations, viral transductions and electroporation of primary cells, to generate CAR T-cells.
• They will also be responsible for CAR T-cells based on current state of the art and novel constructs in vitro and in vivo to identify optimal constructs and characteristics for therapeutic uses
• BS and 5+ years of experience or MS and 3+ years of experience in an academic and/or industrial setting.
• Knowledge and hands-on experience in generating and optimizing human CAR T-cells is required.
• Knowledge and experience of modern laboratory methodology in cellular and molecular T-cell immunology.
• Knowledge and experience with viral based systems (lenti-virus, adenovirus, or murine retrovirus) to optimize transduction of cell-lines and primary cells.
• Knowledge and experience in genome engineering (zinc fingers, TALEN, or CRISPR) is preferred.
• Excellent written, oral communication skills.
• 4-7 years of experience in Biochemical techniques.
• 4-7 years of experience in Cell/Tissue Culture techniques.
Job details are sourced from the employer's original posting.
Open job postingAbout the company
Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.