CRYO-FIB/SEM Staff Scientist, CryoEM Facility, Biology, to lead the adoption of next-generation plasma FIB milling and in situ structural biology as the primary expert for the newly installed HydraBio plasma FIB/SEM; advance cellular and tissue imaging by developing cryo-FIB/ET and volume EM workflows, including fluorescence-guided targeting, precision milling, and lift-out; provide user training, experimental design consultation, and troubleshooting; collaborate on sample preparation, tomography, and data reconstruction; and drive innovative method development and publications; oversee instrument calibration, vendor servicing, and facility infrastructure, including liquid nitrogen and data storage; represent the facility through tours, workshops, and scientific outreach, strengthening cryo-ET and volume EM research across the Cambridge/Boston community.
The full job description is available, here: https://acrobat.adobe.com/id/urn:aaid:sc:US:4001a239-70bd-4d68-837c-15d86f680ace
REQUIRED: Master’s or Ph.D. in biochemistry, structural biology, biophysics, or a closely related discipline; demonstrated hands-on expertise in cryo-FIB milling technology and scanning electron microscopy (SEM); strong foundation in cryogenic sample preparation methods for cells or tissues; exceptional troubleshooting, organizational, and interpersonal skills; and strong commitment to collaborative problem-solving and mentoring a diverse scientific community. Single Particle Analysis (SPA) experience is not required for this role. PREFERRED: A minimum of four years of hands-on research experience in biological electron microscopy; experience with transmission electron microscopy (TEM), particularly with cryo-ET data collection setup on a Titan Krios; background in volume EM, sample lift-out techniques, or cryo-ET data processing workflows, including sub-tomogram averaging (STA); experience diagnosing and resolving FIB/SEM hardware or performance issues; or experience supporting users in a shared research facility.
Must have independent authorization to work in the US. Visa sponsorship is not available.
Revised 6/29/2026
Job details are sourced from the employer's original posting.
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MIT is a private land-grant research university in Cambridge, Massachusetts.