RESEARCH SCIENTIST 3, The Zhang Lab - Broad Institute of MIT and Harvard, with expertise in proteomics and peptidomes. This individual will develop and optimize quantitative and qualitative proteomic, peptidomic, and immunopeptidomic assays supporting research in programmable therapeutics and human health. Key responsibilities include preparing biological samples, operating and maintaining LC-MS instruments, troubleshooting workflows, and analyzing mass spectrometry data using platforms such as PEAKS, FragPipe, DIA-NN, and Skyline. The scientist will lead projects from concept through execution, contribute to experimental design and research strategy, collaborate across teams, and mentor junior researchers.
The full job description is available, here: https://www.dropbox.com/scl/fi/lwyc355ourlsakli1a9yb/Proteomics-Research-Scientist.pdf?rlkey=9m3v8qz6ysozfad42lntkcmyu&st=8yyrb9e1&dl=0
REQUIRED: PhD or equivalent training in proteomics, protein chemistry, molecular biology, analytical chemistry, or a related field; expertise in mass spectrometry-based proteomics or peptidomics; experience developing and optimizing proteomic or peptidomic assays; hands-on experience operating and troubleshooting LC-MS instrumentation; proficiency with PEAKS, FragPipe, DIA-NN, Skyline, or similar software; ability to analyze large datasets and apply appropriate statistical methods; record of scientific productivity through publications, method development, or related contributions; strong experimental design, organization, documentation, and project-management skills; ability to work independently, manage multiple projects, and collaborate effectively; excellent written and verbal communication skills. PREFERRED: Experience with immunopeptidomics and mentoring junior scientists.
9/23/2026
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MIT is a private land-grant research university in Cambridge, Massachusetts.