HireFT
Browse JobsHow it worksPricingAboutSuccess Stories
    Back to jobs
    O2

    o2h Group

    Life Sciences Services

    Research Associate/Senior Research Associate - Peptide/High Potent APIs (HPAPI)/Organic/Antibody Drug Conjugation (ADC)

    Ahmedabad, IndiaOn-SiteFull-time6+ yrs experiencePosted 1w ago
    All o2h Group jobs

    Job description

    High Potent APIs (HPAPI):

    • Perform hands-on laboratory chemistry activities involving high-potency APIs / potent compounds.

    • Execute chemical reactions, work-ups, purification and related laboratory processes.

    • Handle HPAPIs in accordance with applicable safety, containment and handling procedures.

    • Maintain accurate laboratory records, experimental data and documentation.

    • Support process development, optimization and troubleshooting activities.

    • Perform analytical sample preparation and coordinate with analytical teams as required.

    • Follow established GMP, EHS and laboratory safety requirements.

    • Support investigation and resolution of laboratory/process-related issues.

    • Where required, support chemistry activities related to ADC and highly potent payloads.

    • Work effectively with cross-functional teams including analytical and other chemistry groups.

    Organic Chemist:

    • Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance

    • Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography

    • Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations

    • Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

    Peptide Chemist:

    • Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM

    • Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS

    • Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities

    • Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation

    Scaleup Chemist:

    • Experience in process R&D, scale-up synthesis, and purification from gm to kg scale

    • Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities

    • Proficient in 1H NMR, HPLC, and LCMS interpretation

    • Strong project execution and team collaboration skills

    Antibody Drug Conjugation Chemist (ADC)

    • Synthesis and purification of complex antibody drug conjugate (ADC) molecules

    • Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs

    • Synthesis of highly potent drug molecules – payloads

    • Purification of complex and large molecules by flash column and HPLC

    • Handling various type chemistry with different payloads

    • Interpretation and characterisation of higher molecular weight compounds

    Principal Scientist;

    • PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.

    • Strong experience in CRO/CDMO research environment.

    • Proven team management experience with exposure to handling multiple projects.

    • Excellent communication and client-facing skills.

    • Ability to drive productivity, scientific excellence, and team development.

    Organic Chemist:

    • Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry
      Strong organisational, project management and problem-solving skills with impeccable multi-tasking abilities.

    • Proactive, highly motivated with a "can do" attitude

    • Exceptional interpersonal skills.

    Peptide/Scaleup/Antibody Drug Conjugation (ADC) Chemist:

    • Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry

    • Adherence to safe practices and procedures

    • Contribution to the development of safety protocols and systems

    • Must be able to prioritize and organize work responsibilities in order to meet deadlines

    Job details are sourced from the employer's original posting.

    Open job posting
    O2

    About the company

    o2h Group

    o2h Group is a life sciences services group providing drug discovery, chemistry, biology, and technology services to biotech and pharma companies.

    View all o2h Group jobs
    Industry
    Life Sciences Services
    Open roles
    4

    Interested in this role?

    Apply with HireFT

    Free to start — no card required.

    Your fit

    How well do you match?

    Sign in to see how your résumé lines up with this role.