Company Overview:
Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines. Strand is applying its proprietary Signal Stack platform, which integrates EverScript circular RNA, AmpliScript self-replicating RNA, SignalPath targeted delivery, and logic-driven SignalLock genetic circuits to enable precise control of therapeutic activity across tissues and cell types and overcome foundational limitations in targeting, durability, and safety.
Strand is advancing a pipeline with an initial focus on oncology and autoimmune disease. Its initial program, STX-001, an intratumorally delivered LNP-encapsulated self-replicating RNA expressing IL-12, has demonstrated preliminary evidence of systemic immune activation and anti-tumor activity in patients with advanced solid tumors who have progressed on prior therapies. Building on this early clinical validation, intravenously delivered STX-003 is designed for tumor-targeted expression and avoidance of off-target expression. STX-003, which is expected to enter the clinic in mid-2026, has the potential to be a major step forward for the fields of genetic medicine and oncology. Strand is also advancing STX-005, an in vivo CAR-T program designed to enable controlled, durable expression and repeat dosing. Founded by MIT synthetic biology pioneers, Strand has raised over $250 million and is headquartered in Boston, MA.
Become the next standout single strand!
Job Summary:
Strand is seeking a highly motivated and innovative Senior Scientist to join our Process Development team and lead Process Sciences & Innovation across our mRNA platforms.
This role is intended for an experienced lab based technical leader who thrives on solving difficult problems, challenging conventional approaches, and identifying transformative technologies that can fundamentally improve how mRNA products are developed and manufactured. The successful candidate will bring deep expertise in mRNA process development, a strong understanding of emerging technologies, and a passion for translating novel ideas into practical solutions.
Reporting to the Director of Process Development, this individual will serve as the technical lead for Process Sciences & Innovation, partnering closely with Analytical Development and Research, to identify, evaluate, and implement next-generation technologies that enhance process understanding, development efficiency, scalability, and product quality.
The ideal candidate is an intellectually curious scientist who actively seeks out new ideas, remains at the forefront of advances in RNA therapeutics and bioprocessing, and is energized by bringing innovative technologies and concepts into practical application. This role will help shape the future direction of Strand’s mRNA development capabilities.
Primary Responsibilities:
Qualifications:
Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals.
Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.
Job Type: Full-time
Salary: $132,000 - $142,000 annually plus bonus and equity incentives
Pay Transparency Base Salary Range
$132,000 - $142,000 USD
Job details are sourced from the employer's original posting.
Open job postingAbout the company
Strand was founded by biological engineers working together at the Massachusetts Institute of Technology (MIT). Building on the idea of creating smart therapies capable of making sophisticated decisions, they sought to apply this concept to the emerging field of mRNA therapeutics. This area was previously untapped by traditional synthetic biology, leading us to build our very own mRNA programming language, creating the world's first platform for mRNA smart therapies. Strand's mRNA programming technology promises to make mRNA therapies safer and more effective by programming the location, timing, and intensity of therapeutic protein expression inside a patient's body via mRNA-encoded logic circuits. These circuits have the ability to implement cell-type specific expressions by sensing and classifying the unique mRNA expression signatures of cells and control the dosage of protein expression through responses to exogenously administered small molecules.