Salary for this Role:
From £47,080 per annum plus benefits, subject to skills and experience
Job Title:
Senior Laboratory Research ScientistReports to:
Radoslav EnchevClosing Date:
05/Oct/2026 23.59 GMTJob Description:
Senior Laboratory Research Scientist (Senior Protein Biochemist) – Enchev Lab
Contract term: This is a full-time, fixed term (1 year) position on Crick terms and conditions of employment.
Reports to: Radoslav Enchev, Senior Group Leader
About us
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
About the Enchev Lab
The Enchev Lab at the Francis Crick Institute combines experimental structural biology with AI-driven molecular modelling to understand protein-protein interactions and how proteins change shape and function.
The team is building a scalable data engine that brings together high-throughput protein production, state-of-the-art cryo-EM and generative AI to generate high-quality datasets on protein interactions and dynamics. The ambition is to help establish new foundational models for protein dynamics, with applications across fundamental biology and drug discovery.
About the role
We are looking for an experienced and hands-on Senior Protein Biochemist to build and develop the protein production pipeline at the heart of this programme.
You’ll design constructs, express and purify proteins and complexes, develop scalable screening workflows and deliver cryo-EM-ready samples, working closely with structural biologists, computational scientists and engineers.
A key focus will be scale and automation. You’ll develop workflows that can move from small-scale screening to preparative production and help progressively transfer them onto automated liquid-handling platforms.
This is an exciting opportunity to apply your protein biochemistry expertise at the intersection of structural biology, automation and AI-enabled drug discovery.
What you’ll be doing
You will be responsible for:
Click to find out more about the Enchev Lab
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About you
Essential:
Desirable
About Working at the Crick
Our values
Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: [email protected].
Find out more about life at the Crick.
What will you receive?
At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.
We reserve the right to withdraw this advert at any given time due to the number of applications received.
Job details are sourced from the employer's original posting.
Open job postingAbout the company
Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.