Overview
We are looking for an experienced structural biologist with a background in X-ray crystallography to join the growing Structural Biology group based in Munich, Germany. In close collaboration with the various departments at Crelux you will provide structural biology support for early-stage drug discovery projects covering a wide range of target classes. Your main responsibilities will include the planning of structural biology projects and crystallization experiments, X-ray crystallography data processing and structure determination of protein-ligand complexes, and the communication of results to our clients.
Responsibilities
- Planning and running structural biology client projects with a focus on structure-based drug design in early-stage drug discovery projects
- Planning of crystallization and data collection experiments as well as the determination of X-ray crystal structures (typically protein-ligand complexes)
- Professional written and verbal communication of scientific results in internal and external project teams
- Careful documentation and evaluation of scientific protocols and results
- The ability to plan work to meet planned timelines
- Maintain an up-to-date knowledge of scientific advances in structural biology
Qualifications
- PhD in Biology, Biochemistry, Chemistry or a related subject
- Practical and theoretical knowledge of construct design, crystallization, and structure determination using standard software packages (in particular Global Phasing, CCP4, XDS, PyMOL and ChimeraX) running on Linux
- Experience in any of the following areas would be highly advantageous – cryo-electron microscopy, crystallographic fragment screening, protein design
- Experience with programming (Bash and Python), databases (SQL/MariaDB) and/or administration of Linux systems would be a strong advantage
- Excellent interpersonal skills and the ability to work and communicate efficiently in interdisciplinary teams
- Fluent spoken and written English and (ideally) German
